![]() Generally, events resolved after dose reduction or discontinuation of NEUPOGEN ®.Diagnoses were based on azotemia, hematuria, proteinuria, and renal biopsy.Has occurred in patients receiving NEUPOGEN ®.Discontinue NEUPOGEN ® if sickle cell crisis occurs.Severe and sometimes fatal sickle cell crises can occur in patients with sickle cell disorders receiving filgrastim products.Permanently discontinue NEUPOGEN ® in patients with serious allergic reactions.Allergic reactions, including anaphylaxis, in patients receiving NEUPOGEN ® can recur within days after the discontinuation of initial anti-allergic treatment.Provide symptomatic treatment for allergic reactions.Majority of reported events occurred upon initial exposure. ![]()
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